Shikimic Acid hmoov

Shikimic acid yog dab tsi?

Shikimic Acid hmoov yog ib qho dawb crystalline hmoov uas yooj yim soluble hauv dej. Nws muaj npe tom qab nws tau raug rho tawm thawj zaug los ntawm M. japonica thiab yog ib qho tseem ceeb metabolite ntawm cov nroj tsuag thiab cov kab mob. Rau lub sijhawm ntev, shikimic acid tau muab rho tawm los ntawm cov txiv hmab txiv ntoo qhuav thiab paub tab ntawm lub hnub qub anise lossis Japanese shiki (Japanese anise). Nyob rau hauv xyoo tas los no, tseem muaj kev tshawb fawb qhia txog kev rho tawm ntawm shikimic acid los ntawm cov txiv hmab txiv ntoo ntawm North American liquidambar thiab ntoo thuv koob.

Nroj tsuag

Shikimic acid muaj nyob rau hauv cov txiv hmab txiv ntoo qhuav thiab siav ntawm lub hnub qub anise, ib tsob nroj hauv tsev neeg Magnoliaceae. Anise yog tsob ntoo evergreen uas loj hlob nyob rau hauv ib qho chaw ntub dej, ib puag ncig sov so thiab tuaj yeem ncav cuag qhov siab ntawm 30 meters. Feem ntau faib rau thaj chaw roob nrog xoob av hauv Fujian, Guangdong, Guangxi, Yunnan, Guizhou thiab lwm lub xeev. Lub bark yog grey mus reddish xim av. Cov nplooj yog oval, tag nrho-margined, lanceolate hauv kev loj hlob, tawv, luv-stalked, 6-12 cm ntev, 2-5 cm dav, nrog pob tshab roj me ntsis pom nyob rau saum npoo. Blooms nyob rau hauv lub caij nplooj ntoos hlav thiab lub caij nplooj zeeg. Paj yog nyob ib leeg nyob rau hauv nplooj axils. Muaj 3 lub paj daj-ntsuab; 6-9 perianths, liab mus rau tob liab. Txiv hmab txiv ntoo los ntawm lub caij nplooj zeeg mus rau lub caij nplooj ntoos hlav xyoo tom ntej. Cov txiv hmab txiv ntoo sib sau yog lub hnub qub thiab octagonal, 1-2 cm ntev, 3-5 cm dav, thiab <1 cm siab. Nws hloov los ntawm ntsuab mus rau daj thaum paub tab. Sab saum toj ntawm cov hauv paus hniav yog blunt lossis blunt-pointed, thiab txhua tus muaj 6 mm ntev noob. Cov txiv hmab txiv ntoo yog khaws nyob rau hauv lub caij nplooj zeeg thiab lub caij ntuj no thiab tig reddish-xim av los yog daj-xim av tom qab ziab. Qhov tsw yog aromatic thiab qab zib. Mangcao, tseem hu ua qus anise, yog ib tsob ntoo uas muaj tsob ntoo ntsuab txhua xyoo. Cov noob yog lub teeb xim av thiab ci iab. Lub sij hawm flowering yog nyob rau hauv lub Tsib Hlis thiab fruiting lub sij hawm yog los ntawm lub Cuaj Hli Ntuj mus rau Lub kaum hli ntuj. Nws yog tsuas yog faib nyob rau hauv lub hav zoov ntawm barren toj thiab slopes hauv qab no 1200 meters. Nws bears txiv hmab txiv ntoo nyob rau hauv lub caij nplooj zeeg. , txiv hmab txiv ntoo muaj ib tug loj npaum li cas ntawm shikimic acid. Cov txiv hmab txiv ntoo zoo ib yam li lub hnub qub anise, tab sis nws yog tshuaj lom, yog li kev tsis meej pem yuav tsum zam.

Yuav ua li cas yog cov kev pab cuam?

Shikimic Acid hmoov yog ib qho monomeric compound uas muaj cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob, thiab tuaj yeem siv los ua tshuaj tua kab mob nruab nrab. Shikimic acid cuam tshuam cov metabolism ntawm arachidonic acid, inhibits platelet aggregation, thiab inhibits tsim ntawm arterial thiab venous thrombosis thiab cerebral thrombosis. Kev tshawb fawb ua ntej los ntawm Pharmacology Research Laboratory ntawm Beijing University of suav tshuaj tau pom thawj zaug tias shikimic acid muaj cov tshuaj tiv thaiv thrombotic tseem ceeb thiab tuaj yeem tiv thaiv kev tsim cov hlab ntsha thiab cov hlab ntsha thiab cov hlab ntsha hlwb. Txhawm rau elucidate nws cov txheej txheem los tiv thaiv thrombotic, cov kws tshawb fawb tau kawm txog cov nyhuv ntawm shikimic acid ntawm platelet aggregation thiab coagulation, thiab soj ntsuam kev sib raug zoo ntawm nws cov txheej txheem ntawm kev ua thiab arachidonic acid metabolism. Cov txiaj ntsig tau hais tias shikimic acid tuaj yeem tiv thaiv cov kab mob thrombotic los ntawm kev cuam tshuam arachidonic acid metabolism, inhibiting platelet aggregation, thiab inhibiting coagulation system.

(1) Antibacterial nyhuv:

Cov kev tshawb fawb tau tshaj tawm tias cov tshuaj shikimic acid tuaj yeem siv los ua cov khoom qub los ua cov khoom siv ceylon snowflakes (polyoxycyclohexane tshuaj). Cov derivative no tuaj yeem cuam tshuam kev sib kis ntawm nucleotides hauv Eichli ascites qog nqaij hlav cancer thiab muaj kev cuam tshuam rau cov qog nqaij hlav qog noj ntshav hauv vitro. Cells yog tshuaj lom.

(2) Anti-inflammatory thiab analgesic teebmeem:

Los ntawm kev sim tshawb fawb, Xing Jianfeng thiab lwm tus pom tias isopropylshikimic acid (ISA) tsis tuaj yeem tsuas yog inhibit exudation thiab edema nyob rau theem pib ntawm o, tab sis kuj inhibit qhov kev loj hlob ntawm cov ntaub so ntswg thiab tsim ntawm granulation cov ntaub so ntswg nyob rau hauv lub lig theem ntawm o, thiab muaj pom tseeb anti-inflammatory teebmeem.

(3) Anti-thrombotic nyhuv:

Kev tshawb fawb ua ntej los ntawm Pharmacology Research Laboratory ntawm Beijing University of suav tshuaj tau pom thawj zaug tias shikimic acid muaj cov tshuaj tiv thaiv thrombotic tseem ceeb thiab tuaj yeem tiv thaiv kev tsim cov hlab ntsha thiab cov hlab ntsha thiab cov hlab ntsha hlwb. Shikimic acid tuaj yeem tiv thaiv platelet aggregation thiab coagulation system los ntawm kev cuam tshuam arachidonic acid metabolism, yog li ua rau muaj kev tiv thaiv thrombotic.

(4) Anti-avian influenza effect: Oseltamivir (Tamiflu), ib tug neuraminidase inhibitor tsim los ntawm Swiss lub tuam txhab Roche, yog cov tshuaj tiv thaiv kab mob khaub thuas tshiab. Cov kev tshawb fawb sim tau pom tias nws muaj kev cuam tshuam rau cov kab mob khaub thuas avian H5N1 thiab H9N2. , thiab shikimic acid yog ib qho tseem ceeb raw khoom rau cov synthesis ntawm "Tamiflu" thiab tuaj yeem ua ke los ntawm kev hloov kho cov qauv ntawm shikimic acid. Cov tshuaj muaj txiaj ntsig ntawm shikimic acid ua rau nws muaj txiaj ntsig zoo nyiaj txiag.

Daim ntawv thov kev taw qhia

Shikimic Acid hmoov Nws yog ib qho tseem ceeb precursor nyob rau hauv lub synthesis ntawm ntau alkaloids, arylamine acids, indole derivatives thiab chiral tshuaj. Tsis ntev los no, shikimic acid tau siv los ua cov khoom pib rau oseltamivir (cov khoom xyaw nquag ntawm Tamiflu), cov tshuaj neuraminidase inhibitor uas tuaj yeem siv los kho thiab tiv thaiv kab mob khaub thuas A thiab mob khaub thuas B.

Shikimic Acid khoom

Yuantai Organic Bio tau cog lus los muab cov neeg siv khoom zoo tshaj plaws bulk Shikimic Acid hmoov thiab cov kev pabcuam kom txhua tus neeg siv khoom tuaj yeem txaus siab rau tej yam ntuj tso, noj qab nyob zoo, thiab khoom noj khoom haus zoo. Yog tias koj muaj lus nug lossis xav tau ntawm peb cov khoom, thov koj xav tiv tauj peb, thiab peb yuav teb koj sai li sai tau.

Ntim & Xa khoom

Peb lub tuam txhab thiab lub Hoobkas